A comparison of the effects of imposed extension and flexion movements on Parkinsonian rigidity

R. Xia*, K. Markopoulou, S. E. Puumala, W. Z. Rymer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Objective: To test a hypothesis that Parkinsonian rigidity is more pronounced in imposed extension than flexion movement. Methods: Twelve Parkinsonian subjects (both "Off" and "On" medication states) and seven control subjects participated in the protocol, in which a servomotor imposed wrist flexion and extension. Rigidity was quantitatively evaluated by the rectified torque integral with time, i.e., temporal score, and by the torque integral with joint angle, i.e., work score, for extension and flexion, respectively. Results: In the "Off" state, the imposed extension induced a significantly higher resistance than did flexion. Dopaminergic medication significantly reduced the temporal score associated with imposed extension, and significantly decreased the work score of both movements. Compared with controls, the scores were higher for patients in the "On" state. Conclusions: Rigidity is more readily elicited in extension movement. The distinction is not evident in clinical practice, whereas it can be clearly revealed with the application of biomechanical analyses. Significance: This distinction may prove to be a standard feature of rigidity. The procedures may be helpful in diagnosis and useful in evaluating new treatments and developing rehabilitation programs.

Original languageEnglish (US)
Pages (from-to)2302-2307
Number of pages6
JournalClinical Neurophysiology
Volume117
Issue number10
DOIs
StatePublished - Oct 2006

Keywords

  • Dopaminergic medication
  • Extension and flexion movements
  • Objective rigidity score
  • Parkinsonian rigidity
  • Torque-angle relationship

ASJC Scopus subject areas

  • Sensory Systems
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

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