A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease

Cindy Zadikoff, Susan H. Fox, David F. Tang-Wai, Teri Thomsen, Rob M.A. De Bie, Pettarusup Wadia, Janis Miyasaki, Sarah Duff-Canning, Anthony E. Lang, Connie Marras*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

233 Scopus citations

Abstract

Dementia is an important and increasingly recognized problem in Parkinson's disease (PD). The mini-mental state examination (MMSE) often fails to detect early cognitive decline. The Montreal cognitive assessment (MoCA) is a brief tool developed to detect mild cognitive impairment that assesses a broader range of domains frequently affected in PD. The scores on the MMSE and the MoCA were compared in 88 patients with PD. A pronounced ceiling effect was observed with the MMSE but not with the MoCA. The range and standard deviation of scores was larger with the MoCA(7-30, 4.26) than with the MMSE(16-30, 2.55). The percentage of subjects scoring below a cutoff of 26/30 (used by others to detect mild cognitive impairment) was higher on the MoCA (32%) than on the MMSE (11%)(P < 0.000002). Compared to the MMSE, the MoCA may be a more sensitive tool to identify early cognitive impairment in PD.

Original languageEnglish (US)
Pages (from-to)297-299
Number of pages3
JournalMovement Disorders
Volume23
Issue number2
DOIs
StatePublished - Jan 30 2008

Keywords

  • Dementia
  • MMSE
  • Mild cognitive impairment
  • MoCA
  • Parkinson's disease

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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