A comprehensive pipeline for translational top-down proteomics from a single blood draw

Keyphrases

• Blood Draw 100%
• Top-down Proteomics 100%
• Proteoform 66%
• High-throughput 33%
• Translational Research 33%
• High-resolution 33%
• Intact Protein 33%
• Prefractionation 33%
• Mass Spectrometry 16%
• Specimen Preparation 16%
• Biorepository 16%
• Bioinformatics 16%
• Single Sample 16%
• Peripheral Blood Mononuclear Cells 16%
• Clinical Samples 16%
• Proteomic Analysis 16%
• Mass Spectrometer 16%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 16%
• Targeted Analysis 16%
• Electrophoresis 16%
• Cell Preservation 16%
• Cell Lysis 16%
• Proteomic Strategy 16%
• Bottom-up Proteomics 16%
• Lite 16%
• Peptide Mixtures 16%
• Entrapment 16%
• Fourier Transform Mass Spectrometry 16%
• Protein Inference 16%
• Molecular Information 16%
• Storage Scheme 16%
• Minimum Completion Time 16%
• Multiple Workflows 16%
• Instrument Setup 16%

Biochemistry, Genetics and Molecular Biology

• Top-down Proteomics 100%
• Mass Spectrometry 50%
• Fractionation 50%
• Bottom-up Proteomics 16%
• Cytolysis 16%
• Peripheral Blood Mononuclear Cell 16%
• Electrophoresis 16%
• Bioinformatics 16%