A cooperative N-heterocyclic carbene/palladium catalysis system

Kun Liu, M. Todd Hovey, Karl A. Scheidt*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

N-heterocyclic carbenes (NHC) have been extensively studied as organocatalysts and ligands for transition metals, but the successful integration of NHCs and late transition metals in cooperative catalysis remains an underexplored area. We have developed a cooperative palladium-catalyzed allylation of NHC-activated aldehydes to access a variety of 3-allyl dihydrocoumarin derivatives. Kinetic experiments support a cooperative pathway for this transformation.

Original languageEnglish (US)
Pages (from-to)4026-4031
Number of pages6
JournalChemical Science
Volume5
Issue number10
DOIs
StatePublished - Oct 2014

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'A cooperative N-heterocyclic carbene/palladium catalysis system'. Together they form a unique fingerprint.

Cite this