A cooperative N-heterocyclic carbene/palladium catalysis system

Kun Liu; M. Todd Hovey; Karl A. Scheidt

doi:10.1039/c4sc01536c

A cooperative N-heterocyclic carbene/palladium catalysis system

Kun Liu, M. Todd Hovey, Karl A. Scheidt^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

N-heterocyclic carbenes (NHC) have been extensively studied as organocatalysts and ligands for transition metals, but the successful integration of NHCs and late transition metals in cooperative catalysis remains an underexplored area. We have developed a cooperative palladium-catalyzed allylation of NHC-activated aldehydes to access a variety of 3-allyl dihydrocoumarin derivatives. Kinetic experiments support a cooperative pathway for this transformation.

Original language	English (US)
Pages (from-to)	4026-4031
Number of pages	6
Journal	Chemical Science
Volume	5
Issue number	10
DOIs	https://doi.org/10.1039/c4sc01536c
State	Published - Oct 2014

ASJC Scopus subject areas

Chemistry(all)

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10.1039/c4sc01536c

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