A coordination chemistry approach to a multieffector enzyme mimic

Junpei Kuwabara, Charlotte L. Stern, Chad A. Mirkin*

*Corresponding author for this work

Research output: Contribution to journalArticle

54 Scopus citations

Abstract

A macrocyclic complex, formed via the weak-link approach, behaves as a multieffector enzyme mimic in the context of pseudorotaxane formation. The complex has Rh metal centers as regulatory sites, which can be used to change the size and charge of the cavity responsible for pseudorotaxane formation. The first binding events on the metal center (M) involving CO (the filled squares) change the shape of the molecule, while the second binding event involving Cl anion (the filled circles) changes the charge on the molecule and its ability to recognize and sequester a hexyl viologen guest molecule (G).

Original languageEnglish (US)
Pages (from-to)10074-10075
Number of pages2
JournalJournal of the American Chemical Society
Volume129
Issue number33
DOIs
StatePublished - Aug 22 2007

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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