A differentially pumped dual linear quadrupole ion trap (DLQIT) mass spectrometer: A mass spectrometer capable of MSn experiments free from interfering reactions

Benjamin C. Owen, Tiffany M. Jarrell, Jae C. Schwartz, Rob Oglesbee, Mark Carlsen, Enada F. Archibold, Hilkka I. Kenttämaa*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A novel differentially pumped dual linear quadrupole ion trap (DLQIT) mass spectrometer was designed and built to facilitate tandem MS experiments free from interfering reactions. The instrument consists of two differentially pumped Thermo Scientific linear quadrupole ion trap (LQIT) systems that have been connected via an ion transfer octupole encased in a machined manifold. Tandem MS experiments can be performed in the front trap and then the resulting product ions can be transferred via axial ejection into the back trap for further, independent tandem MS experiments in a differentially pumped area. This approach allows the examination of consecutive collision-activated dissociation (CAD) and ion-molecule reactions without unwanted side reactions that often occur when CAD and ion-molecule reactions are examined in the same space. Hence, it greatly facilitates investigations of ion structures. In addition, the overall lower pressure of the DLQIT, as compared to commercial LQIT instruments, results in a reduction of unwanted side reactions with atmospheric contaminants, such as water and oxygen, in CAD and ion-molecule experiments.

Original languageEnglish (US)
Pages (from-to)11284-11290
Number of pages7
JournalAnalytical Chemistry
Volume85
Issue number23
DOIs
StatePublished - Dec 3 2013

ASJC Scopus subject areas

  • Analytical Chemistry

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