A dLight-ful New View of Neuromodulation

Caitlin V. Cosme, Gates K. Palissery, Talia N. Lerner*

*Corresponding author for this work

Research output: Contribution to journalShort survey

Abstract

Neuromodulators such as dopamine can transform neural circuit function, but the mechanisms underlying such transformations are incompletely understood. A recent study introduced dLight1, a genetically encoded fluorescent dopamine indicator. dLight1 allows the optical measurement of dopamine sensed by isolated target circuits with high spatiotemporal resolution and has unique advantages for the study of neuromodulatory mechanisms.

Original languageEnglish (US)
Pages (from-to)566-568
Number of pages3
JournalTrends in Neurosciences
Volume41
Issue number9
DOIs
StatePublished - Sep 2018

Keywords

  • dopamine
  • genetically encoded indicators
  • imaging
  • neuromodulation

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'A dLight-ful New View of Neuromodulation'. Together they form a unique fingerprint.

  • Cite this