A dynamic network perspective of chronic pain

Melissa A. Farmer; Marwan N. Baliki; A. Vania Apkarian

doi:10.1016/j.neulet.2012.05.001

A dynamic network perspective of chronic pain

Melissa A. Farmer, Marwan N. Baliki, A. Vania Apkarian^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

168 Scopus citations

Abstract

We briefly summarize recent advances regarding brain functional representation of chronic pain, reorganization of resting state brain activity, and of brain anatomy with chronic pain. Based on these observations and recent theoretical advances regarding network architecture properties, we develop a general concept of the dynamic interplay between anatomy and function as the brain progresses into persistent pain, and outline the role of mesolimbic learning mechanisms that are likely involved in maintenance of chronic pain.

Original language	English (US)
Pages (from-to)	197-203
Number of pages	7
Journal	Neuroscience Letters
Volume	520
Issue number	2
DOIs	https://doi.org/10.1016/j.neulet.2012.05.001
State	Published - Jun 29 2012

Keywords

Chronic pain
Diffusion tensor imaging
Functional magnetic resonance imaging
Learning
Network
Neuroplasticity

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neulet.2012.05.001

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title = "A dynamic network perspective of chronic pain",

abstract = "We briefly summarize recent advances regarding brain functional representation of chronic pain, reorganization of resting state brain activity, and of brain anatomy with chronic pain. Based on these observations and recent theoretical advances regarding network architecture properties, we develop a general concept of the dynamic interplay between anatomy and function as the brain progresses into persistent pain, and outline the role of mesolimbic learning mechanisms that are likely involved in maintenance of chronic pain.",

keywords = "Chronic pain, Diffusion tensor imaging, Functional magnetic resonance imaging, Learning, Network, Neuroplasticity",

author = "Farmer, {Melissa A.} and Baliki, {Marwan N.} and Apkarian, {A. Vania}",

year = "2012",

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T1 - A dynamic network perspective of chronic pain

AU - Farmer, Melissa A.

AU - Baliki, Marwan N.

AU - Apkarian, A. Vania

PY - 2012/6/29

Y1 - 2012/6/29

N2 - We briefly summarize recent advances regarding brain functional representation of chronic pain, reorganization of resting state brain activity, and of brain anatomy with chronic pain. Based on these observations and recent theoretical advances regarding network architecture properties, we develop a general concept of the dynamic interplay between anatomy and function as the brain progresses into persistent pain, and outline the role of mesolimbic learning mechanisms that are likely involved in maintenance of chronic pain.

AB - We briefly summarize recent advances regarding brain functional representation of chronic pain, reorganization of resting state brain activity, and of brain anatomy with chronic pain. Based on these observations and recent theoretical advances regarding network architecture properties, we develop a general concept of the dynamic interplay between anatomy and function as the brain progresses into persistent pain, and outline the role of mesolimbic learning mechanisms that are likely involved in maintenance of chronic pain.

KW - Chronic pain

KW - Diffusion tensor imaging

KW - Functional magnetic resonance imaging

KW - Learning

KW - Network

KW - Neuroplasticity

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DO - 10.1016/j.neulet.2012.05.001

M3 - Review article

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VL - 520

SP - 197

EP - 203

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 2

ER -

A dynamic network perspective of chronic pain

Abstract

Keywords

ASJC Scopus subject areas

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