TY - JOUR
T1 - {A figure is presented}The Puzzle of Dietary Fat Intake and Risk of Ischemic Stroke
T2 - A Brief Review of Epidemiologic Data
AU - He, Ka
AU - Xu, Youjia
AU - Van Horn, Linda
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/2
Y1 - 2007/2
N2 - While coronary heart disease (CHD) and ischemic stroke share some major risk factors, limited epidemiologic data on dietary fats and vascular disease risk indicate that ischemic stroke is affected differently by these fatty acids than is CHD. The established associations between types of fat and CHD do not appear to apply to ischemic stroke. One explanatory hypothesis for the paradoxical observations is that arteriosclerosis in different types of cerebral arteries has different causal patterns. Fatty acids or blood lipids might not be as important as other factors, such as blood pressure, in the pathogenesis of a certain type of ischemic stroke. However, confirmatory data on the associations of fatty acids and subtype of ischemic stroke, including lacunar, atherosclerotic, and cardioembolic infarction, are lacking. The purpose of this review is to summarize the epidemiologic data on dietary fat and fatty acids in relation to ischemic stroke. Future investigations are needed to examine the effects of fatty acids on subtype of ischemic stroke and to clarify the possible differences of dietary fat in relation to ischemic stroke and CHD.
AB - While coronary heart disease (CHD) and ischemic stroke share some major risk factors, limited epidemiologic data on dietary fats and vascular disease risk indicate that ischemic stroke is affected differently by these fatty acids than is CHD. The established associations between types of fat and CHD do not appear to apply to ischemic stroke. One explanatory hypothesis for the paradoxical observations is that arteriosclerosis in different types of cerebral arteries has different causal patterns. Fatty acids or blood lipids might not be as important as other factors, such as blood pressure, in the pathogenesis of a certain type of ischemic stroke. However, confirmatory data on the associations of fatty acids and subtype of ischemic stroke, including lacunar, atherosclerotic, and cardioembolic infarction, are lacking. The purpose of this review is to summarize the epidemiologic data on dietary fat and fatty acids in relation to ischemic stroke. Future investigations are needed to examine the effects of fatty acids on subtype of ischemic stroke and to clarify the possible differences of dietary fat in relation to ischemic stroke and CHD.
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U2 - 10.1016/j.jada.2006.11.010
DO - 10.1016/j.jada.2006.11.010
M3 - Article
C2 - 17258966
AN - SCOPUS:33846363191
VL - 107
SP - 287
EP - 295
JO - Journal of the Academy of Nutrition and Dietetics
JF - Journal of the Academy of Nutrition and Dietetics
SN - 2212-2672
IS - 2
ER -