A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma

Priya Kumthekar*, Caroline H. Ko, Tatjana Paunesku, Karan Dixit, Adam M. Sonabend, Orin Bloch, Matthew Tate, Margaret Schwartz, Laura Zuckerman, Ray Lezon, Rimas V. Lukas, Borko Jovanovic, Kathleen McCortney, Howard Colman, Si Chen, Barry Lai, Olga Antipova, Junjing Deng, Luxi Li, Serena Tommasini-GhelfiLisa A. Hurley, Dusten Unruh, Nitya V. Sharma, Manoj Kandpal, Fotini M. Kouri, Ramana V. Davuluri, Daniel J. Brat, Miguel Muzzio, Mitchell Glass, Vinod Vijayakumar, Jeremy Heidel, Francis J. Giles, Ann K. Adams, C. David James, Gayle E. Woloschak, Craig Horbinski, Alexander H. Stegh

*Corresponding author for this work

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Medicine & Life Sciences