A G-coupled receptor protein critical for peripheral nerve myelination

Shen Yi B. Howng, Darlene S. Douglas, Brian Popko*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Intercellular signaling between the axon and myelinating glial cells plays an essential role in the regulation of the myelination process. A recent study from Monk et al. has used a forward genetics approach in zebrafish to identify a G protein-coupled receptor that is necessary for Schwann cells to myelinate axons, thereby uncovering a critical component of the axo-glial signaling network.

Original languageEnglish (US)
Pages (from-to)105-106
Number of pages2
JournalJournal of molecular cell biology
Volume2
Issue number3
DOIs
StatePublished - 2010

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology

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