A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping

INIS

• exons 100%
• mice 55%
• genes 55%
• humans 33%
• proteins 33%
• mutations 33%
• limbs 33%
• in vivo 22%
• testing 22%
• muscles 22%
• oligonucleotides 22%
• thymine 22%
• evaluation 11%
• data 11%
• genetics 11%
• therapy 11%
• phenotype 11%
• administration 11%
• nucleotides 11%
• leaks 11%
• point mutations 11%
• residues 11%
• recessive mutations 11%
• corrections 11%

Biochemistry, Genetics and Molecular Biology

• Mutation 44%
• Exon Skipping 44%
• Nested Gene 33%
• Mouse Model 33%
• Antisense 33%
• Sarcoglycan 33%
• Oligonucleotide 22%
• Thymine 22%
• Mouse 22%
• Reading Frame 22%
• Protein 22%
• Muscle Function 11%
• Phenotype 11%
• Protein Expression 11%
• Nucleotide 11%
• Point Mutation 11%
• Autosomal Recessive Inheritance 11%
• Genome Editing 11%
• Gene Structure 11%
• Preclinical Study 11%
• CRISPR/Cas9 11%
• Genetics 11%