A glucose biosensor based on TiO2-Graphene composite

Hee Dong Jang*, Sun Kyung Kim, Hankwon Chang, Ki Min Roh, Jeong Woo Choi, Jiaxing Huang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

202 Scopus citations

Abstract

A novel glucose biosensor was developed based on the adsorption of glucose oxidase at a TiO2-Graphene (GR) nanocomposite electrode. A TiO2-GR composite was synthesized from a colloidal mixture of TiO2 nanparticles and graphene oxide (GO) nanosheets by an aerosol assisted self-assembly (AASA). The particle morphology of all TiO2-GR composites was spherical in shape. It was observed that micron-sized TiO2 particles were encapsulated by GR nanosheets and that the degree of encapsulation was proportional to the ratio of GO/TiO2. The amperometric response of the glucose biosensor fabricated by the TiO2-GR composite was linear against a concentration of glucose ranging from 0 to 8mM at -0.6V. The highest sensitivity was noted at about 6.2μA/mMcm2. The as prepared glucose biosensor based on the TiO2-GR composite showed higher catalytic performance for glucose redox than a pure TiO2 and GR biosensor.

Original languageEnglish (US)
Pages (from-to)184-188
Number of pages5
JournalBiosensors and Bioelectronics
Volume38
Issue number1
DOIs
StatePublished - Oct 2012

Funding

This research was supported by the General Research Project of the Korea Institute of Geoscience and Mineral Resources (KIGAM) funded by the Ministry of Knowledge Economy.

Keywords

  • Aerosol assisted self-assembly
  • Cyclic voltammetry
  • Glucose biosensor
  • TiO-GR composite

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry

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