A group-mediated, home-based physical activity intervention for patients with peripheral artery disease: Effects on social and psychological function

W. J. Rejeski*, Bonnie Spring, Kathryn Domanchuk, Huimin Tao, Lu Tian, Lihui Zhao, Mary M. McDermott

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Background: PAD is a disabling, chronic condition of the lower extremities that affects approximately 8 million people in the United States. The purpose of this study was to determine whether an innovative home-based walking exercise program for patients with peripheral artery disease (PAD) improves self-efficacy for walking, desire for physical competence, satisfaction for physical functioning, social functioning, and acceptance of PAD related pain and discomfort.Methods: The design was a 6-month randomized controlled clinical trial of 194 patients with PAD. Participants were randomized to 1 of 2 parallel groups: a home-based group-mediated cognitive behavioral walking intervention or an attention control condition.Results: Of the 194 participants randomized, 178 completed the baseline and 6-month follow-up visit. The mean age was 70.66 (±9.44) and was equally represented by men and women. Close to half of the cohort was African American. Following 6-months of treatment, the intervention group experienced greater improvement on self-efficacy (p = .0008), satisfaction with functioning (p = .0003), pain acceptance (p = .0002), and social functioning (p = .0008) than the control group; the effects were consistent across a number of potential moderating variables. Change in these outcomes was essentially independent of change in 6-minute walk performance.Trial registration: [ClinicalTrials.gov Identifier: NCT00693940].

Original languageEnglish (US)
Article number29
JournalJournal of Translational Medicine
Volume12
Issue number1
DOIs
StatePublished - Jan 28 2014

Funding

This research was supported by R01-HL088589 and R01-HL107510 from the National Heart, Blood, and Lung Institute. It was also supported in part by the Intramural Research Program at the National Institute of Aging. The first author’s time in preparing this manuscript was supported by a grant from the National Heart, Lung, and Blood Institute, R18 HL076441, and a National Institutes for Aging grant, P30 AG021332.

Keywords

  • Group-mediated intervention
  • Peripheral artery disease
  • Physical activity
  • Psychological function
  • Social function

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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