TY - GEN
T1 - A Hydrogel Microneedle-Based Biosensor for Continuous, Real-Time, and Enzyme-Less Glucose Measurement
AU - GhavamiNejad, Peyman
AU - Dhingra, Karan
AU - GhavamiNejad, Amin
AU - Poudineh, Mahla
N1 - Funding Information:
This research was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery grant.
Publisher Copyright:
© 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Currently, Continuous Glucose Monitors (CGMs) rely on the glucose oxidase enzyme. However, the stability of enzymes is greatly affected by factors such as temperature, which in turn deteriorate the accuracy of CGMs. Here, we introduce the first swellable hydrogel microneedle (MN)-based biosensor for continuous, real-time, enzyme-less, and pain-less glucose sensing. Using a MN-based three electrode system, we detected concentration of glucose ranging from 0 to 20 mM in a skin-mimicking phantom gel.
AB - Currently, Continuous Glucose Monitors (CGMs) rely on the glucose oxidase enzyme. However, the stability of enzymes is greatly affected by factors such as temperature, which in turn deteriorate the accuracy of CGMs. Here, we introduce the first swellable hydrogel microneedle (MN)-based biosensor for continuous, real-time, enzyme-less, and pain-less glucose sensing. Using a MN-based three electrode system, we detected concentration of glucose ranging from 0 to 20 mM in a skin-mimicking phantom gel.
KW - Continuous glucose monitoring
KW - Enzyme-less
KW - Hydrogel
KW - Microneedle
KW - Real-time
UR - http://www.scopus.com/inward/record.url?scp=85136948932&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85136948932&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85136948932
T3 - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 1415
EP - 1416
BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Y2 - 10 October 2021 through 14 October 2021
ER -