A Lethal Convergence of Dopamine and Calcium

D. James Surmeier*

*Corresponding author for this work

Research output: Contribution to journalShort survey

6 Scopus citations

Abstract

The controversy about whether dopamine contributes to cell loss in Parkinson's disease takes a new turn as Mosharov et al. in this issue of Neuron demonstrate that Ca2+ influx through L-type channels elevates dopamine synthesis to potentially toxic levels in vulnerable ventral mesencephalon neurons.

Original languageEnglish (US)
Pages (from-to)163-164
Number of pages2
JournalNeuron
Volume62
Issue number2
DOIs
StatePublished - Apr 30 2009

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ASJC Scopus subject areas

  • Neuroscience(all)

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