A matter of perspective: Comparison of the characteristics of persons with HIV infection in the United States from the HIV outpatient study, medical monitoring project, and National HIV surveillance system

Kate Buchacz*, Emma L. Frazier, H. Irene Hall, Rachel Hart, Ping Huang, Dana Franklin, Xiaohong Hu, Frank J. Palella, Joan S. Chmiel, Richard M. Novak, Kathy Wood, Bienvenido Yangco, Carl Armon, John T. Brooks, Jacek Skarbinski

*Corresponding author for this work

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Comparative analyses of the characteristics of persons living with HIV infection (PLWH) in the United States (US) captured in surveillance and other observational databases are few. To explore potential joint data use to guide HIV treatment and prevention in the US, we examined three CDC-funded data sources in 2012: the HIV Outpatient Study (HOPS), a multisite longitudinal cohort; the Medical Monitoring Project (MMP), a probability sample of PLWH receiving medical care; and the National HIV Surveillance System (NHSS), a surveillance system of all PLWH. Overall, data from 1,697 HOPS, 4,901 MMP, and 865,102 NHSS PLWH were analyzed. Compared with the MMP population, HOPS participants were more likely to be older, non-Hispanic/Latino white, not using injection drugs, insured, diagnosed with HIV before 2009, prescribed antiretroviral therapy, and to have most recent CD4+ T-lymphocyte cell count ≥500 cells/mm3 and most recent viral load test <200 copies/mL. The MMP population was demographically similar to all PLWH in NHSS, except it tended to be slightly older, HIV diagnosed more recently, and to have AIDS. Our comparative results provide an essential first step for combined epidemiologic data analyses to inform HIV care and prevention for PLWH in the US.

Original languageEnglish (US)
Pages (from-to)123-133
Number of pages11
JournalOpen AIDS Journal
Volume9
DOIs
StatePublished - Jan 1 2015

Keywords

  • AIDS
  • Cohort
  • Epidemiology
  • HIV
  • Observational study
  • Surveillance
  • United States

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Virology

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