A model of adaptation in amphibian spindle receptors

James C. Houk; Ronald W. Cornew; Lawrence Stark

doi:10.1016/0022-5193(66)90113-5

A model of adaptation in amphibian spindle receptors

James C. Houk^*, Ronald W. Cornew, Lawrence Stark

^*Corresponding author for this work

Neuroscience

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

A mathematical model, explaining the adaptation commonly seen in the response of amphibian muscle spindle receptors to sudden increases in muscle length, is developed. It is shown that interaction between supposed mechanical properties of the reticulated and dense zones of intrafusal fibers could be the sole source of this adaptation. The model also displays the characteristic response of spindle receptors to intrafusal motor stimulation. The validity of this model appears easily tested.

Original language	English (US)
Pages (from-to)	196-215
Number of pages	20
Journal	Journal of Theoretical Biology
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/0022-5193(66)90113-5
State	Published - Nov 1966

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Agricultural and Biological Sciences(all)
Applied Mathematics

Access to Document

10.1016/0022-5193(66)90113-5

Cite this

@article{8a483437bbe647cbaee0fda4aba4365b,

title = "A model of adaptation in amphibian spindle receptors",

abstract = "A mathematical model, explaining the adaptation commonly seen in the response of amphibian muscle spindle receptors to sudden increases in muscle length, is developed. It is shown that interaction between supposed mechanical properties of the reticulated and dense zones of intrafusal fibers could be the sole source of this adaptation. The model also displays the characteristic response of spindle receptors to intrafusal motor stimulation. The validity of this model appears easily tested.",

author = "Houk, {James C.} and Cornew, {Ronald W.} and Lawrence Stark",

note = "Funding Information: The authors wish to thank Professor Elwood Henneman for reading the manuscript of this paper and for making many helpful suggestions and criticisms. The expenses for this work were met in part by a fellowship from the National Institutes of Health and in part by the following grants: National Institutes of Health NB-3055 and MH-06175; Office of Naval Research Nonr-1841(70).",

year = "1966",

month = nov,

doi = "10.1016/0022-5193(66)90113-5",

language = "English (US)",

volume = "12",

pages = "196--215",

journal = "Journal of Theoretical Biology",

issn = "0022-5193",

publisher = "Academic Press Inc.",

number = "2",

}

TY - JOUR

T1 - A model of adaptation in amphibian spindle receptors

AU - Houk, James C.

AU - Cornew, Ronald W.

AU - Stark, Lawrence

N1 - Funding Information: The authors wish to thank Professor Elwood Henneman for reading the manuscript of this paper and for making many helpful suggestions and criticisms. The expenses for this work were met in part by a fellowship from the National Institutes of Health and in part by the following grants: National Institutes of Health NB-3055 and MH-06175; Office of Naval Research Nonr-1841(70).

PY - 1966/11

Y1 - 1966/11

N2 - A mathematical model, explaining the adaptation commonly seen in the response of amphibian muscle spindle receptors to sudden increases in muscle length, is developed. It is shown that interaction between supposed mechanical properties of the reticulated and dense zones of intrafusal fibers could be the sole source of this adaptation. The model also displays the characteristic response of spindle receptors to intrafusal motor stimulation. The validity of this model appears easily tested.

AB - A mathematical model, explaining the adaptation commonly seen in the response of amphibian muscle spindle receptors to sudden increases in muscle length, is developed. It is shown that interaction between supposed mechanical properties of the reticulated and dense zones of intrafusal fibers could be the sole source of this adaptation. The model also displays the characteristic response of spindle receptors to intrafusal motor stimulation. The validity of this model appears easily tested.

UR - http://www.scopus.com/inward/record.url?scp=0013968917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0013968917&partnerID=8YFLogxK

U2 - 10.1016/0022-5193(66)90113-5

DO - 10.1016/0022-5193(66)90113-5

M3 - Article

C2 - 5972191

AN - SCOPUS:0013968917

SN - 0022-5193

VL - 12

SP - 196

EP - 215

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

IS - 2

ER -

A model of adaptation in amphibian spindle receptors

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this