TY - JOUR
T1 - A mood management intervention in an internet stop smoking randomized controlled trial does not prevent depression
T2 - A cautionary tale
AU - Schueller, Stephen M.
AU - Pérez-Stable, Eliseo J.
AU - Muñoz, Ricardo F.
N1 - Funding Information:
This research program was supported by the Tobacco Related Disease Research Program, the University of California, Office of the President, the Google Adwords Grants Program, and the Brin/Wojcicki Foundation (Muñoz, PI), the Tobacco Research Network Program, Fogarty International Center, National Institute on Drug Abuse, National Institutes of Health, USA (Grant Number TW05935), the National Cancer Institute for Redes en Acción (U01CA86117 and U54CA153511, Pérez-Stable, co-PI), and NIMH Grant F32MH095345 (Schueller, PI).
PY - 2013/10
Y1 - 2013/10
N2 - Smoking and depression are related, and mood management interventions included in smoking cessation interventions can increase smoking abstinence rates. Could a mood management intervention embedded in an Internet-based smoking cessation intervention prevent major depressive episodes? Spanish- and English-speaking smokers (N = 17,430) from 191 countries were randomized to one of four online self-help intervention conditions (two with mood management). We analyzed preventive effects among those participants without a major depressive episode at baseline. The mood management intervention did not reduce the incidence of major depressive episodes in the following 12 months. However, we found a mood management by depression risk interaction (OR = 1.77, p =.004), such that highrisk participants who received the mood management intervention had an increased occurrence of major depressive episodes (32.8% vs. 26.6%), but not low-risk participants (11.6% vs. 10.8%). Further research on whether mood management interventions may have deleterious effects on subsets of smokers appears warranted.
AB - Smoking and depression are related, and mood management interventions included in smoking cessation interventions can increase smoking abstinence rates. Could a mood management intervention embedded in an Internet-based smoking cessation intervention prevent major depressive episodes? Spanish- and English-speaking smokers (N = 17,430) from 191 countries were randomized to one of four online self-help intervention conditions (two with mood management). We analyzed preventive effects among those participants without a major depressive episode at baseline. The mood management intervention did not reduce the incidence of major depressive episodes in the following 12 months. However, we found a mood management by depression risk interaction (OR = 1.77, p =.004), such that highrisk participants who received the mood management intervention had an increased occurrence of major depressive episodes (32.8% vs. 26.6%), but not low-risk participants (11.6% vs. 10.8%). Further research on whether mood management interventions may have deleterious effects on subsets of smokers appears warranted.
KW - Depression
KW - Internet intervention
KW - Prevention
KW - Prevention of depression
KW - Smoking cessation
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U2 - 10.1177/2167702613484717
DO - 10.1177/2167702613484717
M3 - Article
C2 - 25525565
AN - SCOPUS:84890163272
SN - 2167-7026
VL - 1
SP - 401
EP - 412
JO - Clinical Psychological Science
JF - Clinical Psychological Science
IS - 4
ER -