A mood management intervention in an internet stop smoking randomized controlled trial does not prevent depression: A cautionary tale

Stephen M. Schueller, Eliseo J. Pérez-Stable, Ricardo F. Muñoz

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Smoking and depression are related, and mood management interventions included in smoking cessation interventions can increase smoking abstinence rates. Could a mood management intervention embedded in an Internet-based smoking cessation intervention prevent major depressive episodes? Spanish- and English-speaking smokers (N = 17,430) from 191 countries were randomized to one of four online self-help intervention conditions (two with mood management). We analyzed preventive effects among those participants without a major depressive episode at baseline. The mood management intervention did not reduce the incidence of major depressive episodes in the following 12 months. However, we found a mood management by depression risk interaction (OR = 1.77, p =.004), such that highrisk participants who received the mood management intervention had an increased occurrence of major depressive episodes (32.8% vs. 26.6%), but not low-risk participants (11.6% vs. 10.8%). Further research on whether mood management interventions may have deleterious effects on subsets of smokers appears warranted.

Original languageEnglish (US)
Pages (from-to)401-412
Number of pages12
JournalClinical Psychological Science
Volume1
Issue number4
DOIs
StatePublished - Oct 2013

Funding

This research program was supported by the Tobacco Related Disease Research Program, the University of California, Office of the President, the Google Adwords Grants Program, and the Brin/Wojcicki Foundation (Muñoz, PI), the Tobacco Research Network Program, Fogarty International Center, National Institute on Drug Abuse, National Institutes of Health, USA (Grant Number TW05935), the National Cancer Institute for Redes en Acción (U01CA86117 and U54CA153511, Pérez-Stable, co-PI), and NIMH Grant F32MH095345 (Schueller, PI).

Keywords

  • Depression
  • Internet intervention
  • Prevention
  • Prevention of depression
  • Smoking cessation

ASJC Scopus subject areas

  • Clinical Psychology

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