A multiple-domain framework of clinical, economic, and patient-reported outcomes for evaluating benefits of intervention in atopic dermatitis.

Mark Boguniewicz*, William Abramovits, Amy Paller, Diane L. Whitaker-Worth, Mary Prendergast, J. Wang Cheng, Patrick Wang, Kuo B. Tong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Atopic dermatitis (AD) increases health care utilization, affects patient quality of life, places a burden on caregivers, decreases patient/parent productivity, and adds to health care costs. Few studies have examined the effect of specific treatment modalities across a variety of AD-related outcomes. This prospective, multicenter, open-label longitudinal study of adult and pediatric patients with moderate to severe AD was conducted to evaluate the effect of a specific therapeutic intervention on AD-related outcomes over a period of 6 months. Surveys collected physician clinical assessments and patient- and caregiver-reported data across the following domains: clinical outcome, health care utilization/costs, quality of life, physical appearance, productivity/absenteeism, and medication compliance. This study is intended to help guide future research efforts on the net costs and benefits of different interventions across a diverse set of domains and in larger populations.

Original languageEnglish (US)
Pages (from-to)416-423
Number of pages8
JournalJournal of drugs in dermatology : JDD
Volume6
Issue number4
StatePublished - Apr 2007

ASJC Scopus subject areas

  • Dermatology

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