A mussel inspired self-expandable tubular hydrogel with shape memory under NIR for potential biomedical applications

Francis O. Obiweluozor; Amin GhavamiNejad; Bikendra Maharjan; Jinwoo Kim; Chan Hee Park; Cheol Sang Kim

doi:10.1039/c7tb00539c

A mussel inspired self-expandable tubular hydrogel with shape memory under NIR for potential biomedical applications

Francis O. Obiweluozor, Amin GhavamiNejad, Bikendra Maharjan, Jinwoo Kim, Chan Hee Park^*, Cheol Sang Kim

^*Corresponding author for this work

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

We engineered a novel shape memory polymer (SMP), a nanocomposite hydrogel containing polydopamine nanospheres (PDNs) as a self-expandable tubular hydrogel under near-infrared (NIR) irradiation. When NIR is applied to the nanocomposite hydrogel, the PDN nanoparticles absorb light, which is locally dissipated as heat to become the driving force for shape transition behavior. Since the fabricated PDN material has good mechanical properties, including rapid self-expandability and good biocompatibility, when developed with good heating properties under (NIR) irradiation, it might be useful for many biomedical applications such as the treatment of coronary artery disease.

Original language	English (US)
Pages (from-to)	5373-5379
Number of pages	7
Journal	Journal of Materials Chemistry B
Volume	5
Issue number	27
DOIs	https://doi.org/10.1039/c7tb00539c
State	Published - 2017

ASJC Scopus subject areas

General Chemistry
Biomedical Engineering
General Materials Science

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10.1039/c7tb00539c

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title = "A mussel inspired self-expandable tubular hydrogel with shape memory under NIR for potential biomedical applications",

abstract = "We engineered a novel shape memory polymer (SMP), a nanocomposite hydrogel containing polydopamine nanospheres (PDNs) as a self-expandable tubular hydrogel under near-infrared (NIR) irradiation. When NIR is applied to the nanocomposite hydrogel, the PDN nanoparticles absorb light, which is locally dissipated as heat to become the driving force for shape transition behavior. Since the fabricated PDN material has good mechanical properties, including rapid self-expandability and good biocompatibility, when developed with good heating properties under (NIR) irradiation, it might be useful for many biomedical applications such as the treatment of coronary artery disease.",

author = "Obiweluozor, {Francis O.} and Amin GhavamiNejad and Bikendra Maharjan and Jinwoo Kim and Park, {Chan Hee} and Kim, {Cheol Sang}",

note = "Funding Information: This research was supported by grants from the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education, Science and Technology (Project no. 2013R1A2A2A04015484). Publisher Copyright: {\textcopyright} 2017 The Royal Society of Chemistry.",

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AU - Obiweluozor, Francis O.

AU - GhavamiNejad, Amin

AU - Maharjan, Bikendra

AU - Kim, Jinwoo

AU - Park, Chan Hee

AU - Kim, Cheol Sang

N1 - Funding Information: This research was supported by grants from the Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education, Science and Technology (Project no. 2013R1A2A2A04015484). Publisher Copyright: © 2017 The Royal Society of Chemistry.

PY - 2017

Y1 - 2017

N2 - We engineered a novel shape memory polymer (SMP), a nanocomposite hydrogel containing polydopamine nanospheres (PDNs) as a self-expandable tubular hydrogel under near-infrared (NIR) irradiation. When NIR is applied to the nanocomposite hydrogel, the PDN nanoparticles absorb light, which is locally dissipated as heat to become the driving force for shape transition behavior. Since the fabricated PDN material has good mechanical properties, including rapid self-expandability and good biocompatibility, when developed with good heating properties under (NIR) irradiation, it might be useful for many biomedical applications such as the treatment of coronary artery disease.

AB - We engineered a novel shape memory polymer (SMP), a nanocomposite hydrogel containing polydopamine nanospheres (PDNs) as a self-expandable tubular hydrogel under near-infrared (NIR) irradiation. When NIR is applied to the nanocomposite hydrogel, the PDN nanoparticles absorb light, which is locally dissipated as heat to become the driving force for shape transition behavior. Since the fabricated PDN material has good mechanical properties, including rapid self-expandability and good biocompatibility, when developed with good heating properties under (NIR) irradiation, it might be useful for many biomedical applications such as the treatment of coronary artery disease.

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A mussel inspired self-expandable tubular hydrogel with shape memory under NIR for potential biomedical applications

Abstract

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