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A new class of conformationally rigid analogues of 4-amino-5- halopentanoic acids, potent inactivators of γ-aminobutyric acid aminotransferase
Jian Qiu,
Richard B. Silverman
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Corresponding author for this work
Chemistry
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Article
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peer-review
119
Scopus citations
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Dive into the research topics of 'A new class of conformationally rigid analogues of 4-amino-5- halopentanoic acids, potent inactivators of γ-aminobutyric acid aminotransferase'. Together they form a unique fingerprint.
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Chemistry
Acid
100%
Gamma-Aminobutyric Acid
100%
Rate
50%
Ion
33%
Fluoride
33%
Halogen
33%
Rate Constant
16%
Hydrogen Bond
16%
Deuterium(.)
16%
Urea
16%
Vigabatrin
16%
Enamine
16%
Size Exclusion Chromatography
16%
Denaturation
16%
Radioactivity
16%
Chemical Bond
16%
Rate-Determining Step
16%
Michael Addition
16%
Potential
16%
Isotope Effect
16%
INIS
inactivation
100%
aminotransferases
100%
aminobutyric acid
100%
chains
37%
ions
25%
cleavage
25%
fluorides
25%
halogens
25%
constraints
12%
filtration
12%
gels
12%
accounting
12%
enzymes
12%
residues
12%
reaction kinetics
12%
deuterium
12%
urea
12%
isotope effects
12%
radioactivity
12%