A New Direction for Gene Looping

Carlo E. Randise-Hinchliff; Jason H. Brickner

doi:10.1016/j.devcel.2012.10.024

A New Direction for Gene Looping

Carlo E. Randise-Hinchliff, Jason H. Brickner^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Upon binding to a promoter, RNA polymerase II can synthesize either a coding mRNA or a divergently transcribed noncoding RNA. In a recent issue of Science, Tan-Wong et al. (2012) find that intragenic looping increases the proper orientation of RNA polymerase II, reducing the production of divergent noncoding transcripts.

Original language	English (US)
Pages (from-to)	919-921
Number of pages	3
Journal	Developmental Cell
Volume	23
Issue number	5
DOIs	https://doi.org/10.1016/j.devcel.2012.10.024
State	Published - Nov 13 2012

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
Molecular Biology
Cell Biology
Developmental Biology

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10.1016/j.devcel.2012.10.024

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@article{3392ed53b003489cb20701171c339d8d,

title = "A New Direction for Gene Looping",

abstract = "Upon binding to a promoter, RNA polymerase II can synthesize either a coding mRNA or a divergently transcribed noncoding RNA. In a recent issue of Science, Tan-Wong et al. (2012) find that intragenic looping increases the proper orientation of RNA polymerase II, reducing the production of divergent noncoding transcripts.",

author = "Randise-Hinchliff, {Carlo E.} and Brickner, {Jason H.}",

year = "2012",

month = nov,

day = "13",

doi = "10.1016/j.devcel.2012.10.024",

language = "English (US)",

volume = "23",

pages = "919--921",

journal = "Developmental Cell",

issn = "1534-5807",

publisher = "Cell Press",

number = "5",

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T1 - A New Direction for Gene Looping

AU - Randise-Hinchliff, Carlo E.

AU - Brickner, Jason H.

PY - 2012/11/13

Y1 - 2012/11/13

N2 - Upon binding to a promoter, RNA polymerase II can synthesize either a coding mRNA or a divergently transcribed noncoding RNA. In a recent issue of Science, Tan-Wong et al. (2012) find that intragenic looping increases the proper orientation of RNA polymerase II, reducing the production of divergent noncoding transcripts.

AB - Upon binding to a promoter, RNA polymerase II can synthesize either a coding mRNA or a divergently transcribed noncoding RNA. In a recent issue of Science, Tan-Wong et al. (2012) find that intragenic looping increases the proper orientation of RNA polymerase II, reducing the production of divergent noncoding transcripts.

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DO - 10.1016/j.devcel.2012.10.024

M3 - Short survey

C2 - 23153489

AN - SCOPUS:84869059051

SN - 1534-5807

VL - 23

SP - 919

EP - 921

JO - Developmental Cell

JF - Developmental Cell

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ER -

A New Direction for Gene Looping

Abstract

ASJC Scopus subject areas

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