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A New Era for an Ancient Drug. Arsenic Trioxide and Hedgehog Signaling
Elspeth M. Beauchamp
*
, Aykut Üren
*
Corresponding author for this work
Medicine, Hematology Oncology Division
Research output
:
Contribution to journal
›
Article
›
peer-review
29
Scopus citations
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Keyphrases
Hedgehog Signaling
100%
Arsenic
100%
Arsenic Trioxide
100%
Hedgehog Signaling Pathway
66%
Cysteine Residues
66%
Mitogen-activated Protein Kinase
33%
Therapeutic Agents
33%
Mechanism of Action
33%
FDA-approved Drugs
33%
Thiol Groups
33%
Binding Site
33%
Direct Binding
33%
Fusion Protein
33%
Alternative Therapy
33%
Acquired Resistance
33%
Basal Cell Carcinoma
33%
Zinc Finger
33%
Rhabdoid Tumor
33%
Medulloblastoma
33%
Acute Promyelocytic Leukemia
33%
Thioredoxin Reductase
33%
Ewing Sarcoma
33%
PML-RAR
33%
Hedgehog Inhibitor
33%
Medicine and Dentistry
Arsenic Trioxide
100%
Hedgehog Signaling
100%
Cysteine
50%
Acute Promyelocytic Leukemia
25%
Therapeutic Agent
25%
Malignant Neoplasm
25%
Zinc Finger Motif
25%
Medulloblastoma
25%
Granulocyte
25%
Fusion Protein
25%
Basal-Cell Carcinoma
25%
Rhabdoid Tumor
25%
Ewing Sarcoma
25%
Thiol Group
25%
Thioredoxin Reductase
25%
Binding Site
25%
Mitogen-Activated Protein Kinase
25%
Pharmacology, Toxicology and Pharmaceutical Science
Hedgehog
100%
Arsenite
100%
Cysteine
50%
Malignant Neoplasm
25%
Thiol Group
25%
Binding Site
25%
Fusion Protein
25%
Zinc Finger Protein
25%
Basal Cell Carcinoma
25%
Rhabdoid Tumor
25%
Ewing Sarcoma
25%
Promyelocytic Leukemia
25%
Thioredoxin Reductase
25%
Medulloblastoma
25%