A new piece in the nephrotic puzzle

Susan E. Quaggin

doi:10.1038/ng1206-1360

A new piece in the nephrotic puzzle

Susan E. Quaggin^*

^*Corresponding author for this work

Medicine, Nephrology Division

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

A new study reports mutations in PLCE1 responsible for an autosomal recessive nephrotic syndrome in children that presents with diffuse mesangial sclerosis or focal segmental glomerulosclerosis. Remarkably, two affected individuals treated at an early phase of life responded to either steroids or cyclosporin A, opening a window of opportunity for therapy.

Original language	English (US)
Pages (from-to)	1360-1361
Number of pages	2
Journal	Nature Genetics
Volume	38
Issue number	12
DOIs	https://doi.org/10.1038/ng1206-1360
State	Published - Dec 5 2006

ASJC Scopus subject areas

Genetics

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10.1038/ng1206-1360

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abstract = "A new study reports mutations in PLCE1 responsible for an autosomal recessive nephrotic syndrome in children that presents with diffuse mesangial sclerosis or focal segmental glomerulosclerosis. Remarkably, two affected individuals treated at an early phase of life responded to either steroids or cyclosporin A, opening a window of opportunity for therapy.",

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A new piece in the nephrotic puzzle

Abstract

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