A new player SETs in myeloid malignancy

Thomas Trimarchi, Panagiotis Ntziachristos, Iannis Aifantis

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Recent studies have identified recurrent mutations in SETBP1, the gene that encodes SET-binding protein 1, in several types of myeloid malignancies, including chronic myeloid and acute myeloid leukemias. The identified mutations frequently target the SKI-homologous domain, although the exact pathogenic mechanisms remain unknown.

Original languageEnglish (US)
Pages (from-to)846-847
Number of pages2
JournalNature Genetics
Volume45
Issue number8
DOIs
StatePublished - Aug 2013

ASJC Scopus subject areas

  • Genetics

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