A new player SETs in myeloid malignancy

Thomas Trimarchi; Panagiotis Ntziachristos; Iannis Aifantis

doi:10.1038/ng.2709

A new player SETs in myeloid malignancy

Thomas Trimarchi, Panagiotis Ntziachristos, Iannis Aifantis

Biochemistry and Molecular Genetics

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Recent studies have identified recurrent mutations in SETBP1, the gene that encodes SET-binding protein 1, in several types of myeloid malignancies, including chronic myeloid and acute myeloid leukemias. The identified mutations frequently target the SKI-homologous domain, although the exact pathogenic mechanisms remain unknown.

Original language	English (US)
Pages (from-to)	846-847
Number of pages	2
Journal	Nature Genetics
Volume	45
Issue number	8
DOIs	https://doi.org/10.1038/ng.2709
State	Published - Aug 2013

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ASJC Scopus subject areas

Genetics

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title = "A new player SETs in myeloid malignancy",

abstract = "Recent studies have identified recurrent mutations in SETBP1, the gene that encodes SET-binding protein 1, in several types of myeloid malignancies, including chronic myeloid and acute myeloid leukemias. The identified mutations frequently target the SKI-homologous domain, although the exact pathogenic mechanisms remain unknown.",

author = "Thomas Trimarchi and Panagiotis Ntziachristos and Iannis Aifantis",

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AB - Recent studies have identified recurrent mutations in SETBP1, the gene that encodes SET-binding protein 1, in several types of myeloid malignancies, including chronic myeloid and acute myeloid leukemias. The identified mutations frequently target the SKI-homologous domain, although the exact pathogenic mechanisms remain unknown.

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A new player SETs in myeloid malignancy

Abstract

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