A nipple-valve technique for ureteroneocystostomy in pediatric kidney transplantation

Kyle J. Van Arendonk, Seth D. Goldstein, Jose H. Salazar, Komal Kumar, Henry T. Lau, Paul M. Colombani

Research output: Contribution to journalArticle

2 Scopus citations


The ureteroneocystostomy in kidney transplantation can be performed with a variety of techniques. Over a 20-yr period, we utilized a technique of nipple-valve ureteroneocystostomy for the pediatric kidney transplants performed at our institution. The distal ureter is everted upon itself and anchored in place with four interrupted sutures to create a nipple valve, which is then inserted into the bladder and sewn mucosa-to-mucosa with the same sutures. The muscularis layer is closed around the ureter without tunneling and without routine ureteral stenting. After 109 transplants, patient survival was 97.2, 97.2, and 86.9% at one, five, and 10 yr, respectively. Graft survival was 91.7, 71.7, and 53.9% at one, five, and 10 yr, respectively. The most common cause of graft loss was acute or chronic rejection, seen in 75% of those experiencing graft loss. Two patients (1.8%) developed pyelonephritis in the transplanted kidney. Nipple-valve ureteroneocystostomy in pediatric kidney transplantation is a safe and simple method for performing the ureterovesical anastomosis with a low rate of pyelonephritis after transplantation.

Original languageEnglish (US)
Pages (from-to)42-47
Number of pages6
JournalPediatric Transplantation
Issue number1
Publication statusPublished - Jan 1 2015



  • pediatric kidney transplantation
  • surgery
  • surgical complications
  • ureter
  • vesicoureteral reflux

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

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