A novel and personalized rehabilitation program for obese kidney transplant recipients

I. Tzvetanov, P. West-Thielke, G. D'Amico, M. Johnsen, A. Ladik, G. Hachaj, M. Grazman, R. U. Heller, B. Fernhall, M. L. Daviglus, R. J. Solaro, J. Oberholzer, L. Gallon, E. Benedetti*

*Corresponding author for this work

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Introduction. Physical rehabilitation programs for kidney transplant recipients are not routinely personalized to patients' physical and emotional health, which could result in a potentially limited health impact, shorter-term participation, and an overall low success rate. Materials and Methods. We conducted an internal review boardeapproved randomized prospective study involving a 12-month supervised multidisciplinary rehabilitation program (GH method) initiated after kidney transplantation in obese recipients (body mass index >30). The new method incorporates 3 major components: physical exercise, behavioral interventions, and nutritional guidance. We compared 9 patients who underwent supervised rehabilitation with 8 patients who underwent standard care. Patients were followed up after the start of the intervention, and multiple assessments were performed. Results. The adherence to training and follow-up was 100% in the intervention group, compared with 25% at 12 months in the control group. There was a trend for a higher glomerular filtration rate in the intervention group compared with the control group (55.5 ± 18.6 mL/min/1.73 m2 vs 38.8 ± 18.9 mL/min/1.73 m2, P = .06). The quality of life (SF-36) mean score improved more in the intervention group compared with the control group (583 ± 13 vs 436 ± 22, P = .008). There was a significantly higher employment rate in the intervention group, 77.7% at 12 months compared with 12.5% in the control group (P = .02). Conclusions. Our preliminary results suggest that this comprehensive approach to physical rehabilitation can improve adherence, kidney function, quality of life, and employment rate for obese patients after kidney transplantation.

Original languageEnglish (US)
Pages (from-to)3431-3437
Number of pages7
JournalTransplantation proceedings
Volume46
Issue number10
DOIs
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Fingerprint Dive into the research topics of 'A novel and personalized rehabilitation program for obese kidney transplant recipients'. Together they form a unique fingerprint.

  • Cite this

    Tzvetanov, I., West-Thielke, P., D'Amico, G., Johnsen, M., Ladik, A., Hachaj, G., Grazman, M., Heller, R. U., Fernhall, B., Daviglus, M. L., Solaro, R. J., Oberholzer, J., Gallon, L., & Benedetti, E. (2014). A novel and personalized rehabilitation program for obese kidney transplant recipients. Transplantation proceedings, 46(10), 3431-3437. https://doi.org/10.1016/j.transproceed.2014.05.085