A novel device for in vitro isometric tension recordings of cylindrical artery segments

Joseph B. Young, Babak S. Jahromi, Zhen Du Zhang, R. Loch Macdonald*

*Corresponding author for this work

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

There are few instruments specifically designed to measure circumferential force generated by ring segments of arteries in vitro. Typical limitations of some existing machines include poor isometry, large organ bath volume or difficult sample mounting. The authors designed, built and tested a device for isometric tension recording of force developed by rings of arteries in vitro. It is suitable for assessment of arteries from 0.3 to 3 mm in diameter and allows measurements of forces in the range 0-20 g on eight rings simultaneously. The organ baths are independently regulated in temperature, stirred, disposable and have a minimum useable volume of only 1.2 mL.

Original languageEnglish (US)
Pages (from-to)169-174
Number of pages6
JournalMedical Engineering and Physics
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2007

Fingerprint

Mountings
Arteries
Baths
Equipment and Supplies
Organ Size
Temperature
In Vitro Techniques

Keywords

  • Cerebral vasospasm
  • Isometric tension recording
  • Subarachnoid hemorrhage

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering

Cite this

Young, Joseph B. ; Jahromi, Babak S. ; Zhang, Zhen Du ; Macdonald, R. Loch. / A novel device for in vitro isometric tension recordings of cylindrical artery segments. In: Medical Engineering and Physics. 2007 ; Vol. 29, No. 1. pp. 169-174.
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A novel device for in vitro isometric tension recordings of cylindrical artery segments. / Young, Joseph B.; Jahromi, Babak S.; Zhang, Zhen Du; Macdonald, R. Loch.

In: Medical Engineering and Physics, Vol. 29, No. 1, 01.01.2007, p. 169-174.

Research output: Contribution to journalArticle

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