A pilot study of the nutritional status of opiate-using pregnant women on methadone maintenance therapy

Laura Elizabeth Tomedi*, Debra L. Bogen, Barbara H. Hanusa, Katherine L. Wisner, Lisa M. Bodnar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Pregnant women in methadone maintenance therapy may have poor nutrition during pregnancy. In 20062008, methadone-treated pregnant women (n = 22) were recruited at an urban academic medical center and compared with nondrug-using pregnant women (n = 119) at 2035 weeks' gestation. We measured adiposity using prepregnancy body mass index (BMI), dietary intake using a food frequency questionnaire, and micronutrient and essential fatty acid status using biomarkers. Methadone-treated women had lower BMI, consumed more calories, had lower serum carotenoid concentrations, and higher plasma homocysteine concentrations than controls. The study's limitations and implications for future research are discussed.

Original languageEnglish (US)
Pages (from-to)286-295
Number of pages10
JournalSubstance Use and Misuse
Volume47
Issue number3
DOIs
StatePublished - Feb 2012

Funding

This study was funded by the Children’s Hospital of Pittsburgh Research Advisory Committee and the Gerber Foundation. Study visits were conducted in the Magee-Womens Hospital Clinical and Translational Research Center, which is funded by National Institutes of Health (NIH; grant MO1RR00056). The authors’ contributions to this work were supported by K12 HD043441 [Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) Award], NIH/NIMH (National Institute of Mental Health) grants R01 MH060335 and K01 MH074092, and the Reproductive, Perinatal and Pediatric Epidemiology grant HD 055 162-03 NIH NRSA T32 [National Institute of Child Health and Human Development (NICHD)]. 1The journal’s style utilizes the category substance abuse as a diagnostic category. Substances are used or misused; living organisms are and can be abused. Editor’s note. Address correspondence to Laura Elizabeth Tomedi, M.P.H., Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; E-mail: [email protected]

Keywords

  • Dietary intake
  • Methadone
  • Nutrition
  • Nutritional biomarkers
  • Obesity
  • Pregnancy

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health
  • Medicine (miscellaneous)

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