A pilot study of vitamin D, calcium, and percent breast density in Hispanic women

Laura A. Colangelo; Brian C.H. Chiu; Pilar Lopez; Denise Scholtens; Laura C. Willis; R. Edward Hendrick; Susan M. Gapstur

doi:10.1016/j.nutres.2005.11.001

A pilot study of vitamin D, calcium, and percent breast density in Hispanic women

Laura A. Colangelo^*, Brian C.H. Chiu, Pilar Lopez, Denise Scholtens, Laura C. Willis, R. Edward Hendrick, Susan M. Gapstur

^*Corresponding author for this work

Preventive Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

No studies have examined the associations of vitamin D and calcium intake with mammographic breast density in Hispanic women. Using the Southwest Food Frequency Questionnaire, we investigated these associations in a sample of 99 Hispanic women from the Chicago Breast Health Project Phase II Pilot Study. Using cutpoints based on recommended daily allowances, we classified women according to their intake status as low, medium, or high and compared adjusted mean percent density and dense area across the intake groups. Mean percent densities were 22.0%, 20.3%, and 9.6%, respectively, in the low, medium, and high intake groups for dietary vitamin D (P = .009). Inverse associations also were observed when the analysis was stratified by menopausal status. Total dense area was weakly and inversely associated with intake of dietary vitamin D (P = .1). There were no other meaningful associations. These results support previous findings of inverse associations between dietary vitamin D and breast density.

Original language	English (US)
Pages (from-to)	11-15
Number of pages	5
Journal	Nutrition Research
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/j.nutres.2005.11.001
State	Published - Jan 2006

Funding

This research was supported by the Special Programs of Research Excellence (SPORE) in Breast Cancer, National Cancer Institute grant no. P50 CA89018. The Avon Foundation and the Carol Gollob Foundation also provided financial support of this project.

Keywords

Breast cancer
Calcium
Hispanic women
Mammographic breast density
Vitamin D

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Nutrition and Dietetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.nutres.2005.11.001

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title = "A pilot study of vitamin D, calcium, and percent breast density in Hispanic women",

abstract = "No studies have examined the associations of vitamin D and calcium intake with mammographic breast density in Hispanic women. Using the Southwest Food Frequency Questionnaire, we investigated these associations in a sample of 99 Hispanic women from the Chicago Breast Health Project Phase II Pilot Study. Using cutpoints based on recommended daily allowances, we classified women according to their intake status as low, medium, or high and compared adjusted mean percent density and dense area across the intake groups. Mean percent densities were 22.0%, 20.3%, and 9.6%, respectively, in the low, medium, and high intake groups for dietary vitamin D (P = .009). Inverse associations also were observed when the analysis was stratified by menopausal status. Total dense area was weakly and inversely associated with intake of dietary vitamin D (P = .1). There were no other meaningful associations. These results support previous findings of inverse associations between dietary vitamin D and breast density.",

keywords = "Breast cancer, Calcium, Hispanic women, Mammographic breast density, Vitamin D",

author = "Colangelo, {Laura A.} and Chiu, {Brian C.H.} and Pilar Lopez and Denise Scholtens and Willis, {Laura C.} and Hendrick, {R. Edward} and Gapstur, {Susan M.}",

note = "Funding Information: This research was supported by the Special Programs of Research Excellence (SPORE) in Breast Cancer, National Cancer Institute grant no. P50 CA89018. The Avon Foundation and the Carol Gollob Foundation also provided financial support of this project.",

year = "2006",

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doi = "10.1016/j.nutres.2005.11.001",

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AU - Colangelo, Laura A.

AU - Chiu, Brian C.H.

AU - Lopez, Pilar

AU - Scholtens, Denise

AU - Willis, Laura C.

AU - Hendrick, R. Edward

AU - Gapstur, Susan M.

N1 - Funding Information: This research was supported by the Special Programs of Research Excellence (SPORE) in Breast Cancer, National Cancer Institute grant no. P50 CA89018. The Avon Foundation and the Carol Gollob Foundation also provided financial support of this project.

PY - 2006/1

Y1 - 2006/1

N2 - No studies have examined the associations of vitamin D and calcium intake with mammographic breast density in Hispanic women. Using the Southwest Food Frequency Questionnaire, we investigated these associations in a sample of 99 Hispanic women from the Chicago Breast Health Project Phase II Pilot Study. Using cutpoints based on recommended daily allowances, we classified women according to their intake status as low, medium, or high and compared adjusted mean percent density and dense area across the intake groups. Mean percent densities were 22.0%, 20.3%, and 9.6%, respectively, in the low, medium, and high intake groups for dietary vitamin D (P = .009). Inverse associations also were observed when the analysis was stratified by menopausal status. Total dense area was weakly and inversely associated with intake of dietary vitamin D (P = .1). There were no other meaningful associations. These results support previous findings of inverse associations between dietary vitamin D and breast density.

AB - No studies have examined the associations of vitamin D and calcium intake with mammographic breast density in Hispanic women. Using the Southwest Food Frequency Questionnaire, we investigated these associations in a sample of 99 Hispanic women from the Chicago Breast Health Project Phase II Pilot Study. Using cutpoints based on recommended daily allowances, we classified women according to their intake status as low, medium, or high and compared adjusted mean percent density and dense area across the intake groups. Mean percent densities were 22.0%, 20.3%, and 9.6%, respectively, in the low, medium, and high intake groups for dietary vitamin D (P = .009). Inverse associations also were observed when the analysis was stratified by menopausal status. Total dense area was weakly and inversely associated with intake of dietary vitamin D (P = .1). There were no other meaningful associations. These results support previous findings of inverse associations between dietary vitamin D and breast density.

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A pilot study of vitamin D, calcium, and percent breast density in Hispanic women

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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