A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13

C. E. Schwartz; E. McNally; Leslie Leinwand; M. H. Skolnick

doi:10.1159/000132307

A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13

C. E. Schwartz, E. McNally, Leslie Leinwand^*, M. H. Skolnick

^*Corresponding author for this work

Medicine, Cardiology Division

Research output: Contribution to journal › Article › peer-review

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Abstract

Restriction fragment length polymorphisms (RELPs) have been developed for an adult human skeletal muscle myosin heavy chain gene which was previously mapped to the short arm of human chromosome 17. Using RELP analysis of DNA from 140 individuals, we have found tight linkage (LOD score of 6.9) between this myosin heavy chain gene and the anonymous DNA probe. DI7S1.

Original language	English (US)
Pages (from-to)	117-120
Number of pages	4
Journal	Cytogenetic and Genome Research
Volume	43
Issue number	1-2
DOIs	https://doi.org/10.1159/000132307
State	Published - 1986

ASJC Scopus subject areas

Molecular Biology
Genetics
Genetics(clinical)

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title = "A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13",

abstract = "Restriction fragment length polymorphisms (RELPs) have been developed for an adult human skeletal muscle myosin heavy chain gene which was previously mapped to the short arm of human chromosome 17. Using RELP analysis of DNA from 140 individuals, we have found tight linkage (LOD score of 6.9) between this myosin heavy chain gene and the anonymous DNA probe. DI7S1.",

author = "Schwartz, {C. E.} and E. McNally and Leslie Leinwand and Skolnick, {M. H.}",

year = "1986",

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AU - McNally, E.

AU - Leinwand, Leslie

AU - Skolnick, M. H.

PY - 1986

Y1 - 1986

N2 - Restriction fragment length polymorphisms (RELPs) have been developed for an adult human skeletal muscle myosin heavy chain gene which was previously mapped to the short arm of human chromosome 17. Using RELP analysis of DNA from 140 individuals, we have found tight linkage (LOD score of 6.9) between this myosin heavy chain gene and the anonymous DNA probe. DI7S1.

AB - Restriction fragment length polymorphisms (RELPs) have been developed for an adult human skeletal muscle myosin heavy chain gene which was previously mapped to the short arm of human chromosome 17. Using RELP analysis of DNA from 140 individuals, we have found tight linkage (LOD score of 6.9) between this myosin heavy chain gene and the anonymous DNA probe. DI7S1.

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A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13

Abstract

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