A possible mechanism for neurologic ischemic events in patients with atrial septal aneurysm

Miguel Zabalgoitia-Reyes*, Cesar Herrera, Dipeshkumar K. Gandhi, David J. Mehlman, David D. McPherson, James V. Talano

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Abstract

A trial septal aneurysm (ASA) is a congenital malformation of the atrial septum that has been associated, among other conditions, with transient ischemic attacks and strokes.1-5 The nature of this relation is unclear. Embolic events have been attributed to thrombus formation in or at the base of the aneurysmal sac.5,6 However, the possibility of an associated functionally patent foramen ovale leading to a paradoxical embolus from a right-to-left shunting also has been suggested.2-4 To help clarify this issue, we analyzed the morphologic and functional characteristics of the atrial septum in patients with ASA by the use of transesophageal contrast echocardiography.

Original languageEnglish (US)
Pages (from-to)761-764
Number of pages4
JournalThe American journal of cardiology
Volume66
Issue number7
DOIs
StatePublished - Sep 15 1990

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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