A predictive model for preterm babies born < 30 weeks gestational age who will not attain full oral feedings

Daniel B. Gehle, Alison Chapman, Mathew Gregoski, Meghan Brunswick, Emily Anderson, Viswanathan Ramakrishnan, Lutfiyya N. Muhammad, William Head, Aaron P. Lesher*, Rita M. Ryan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objective: Develop a model to predict gastrostomy tube (GT) for feeding at discharge in infants born < 30 weeks’ (w) gestational age (GA). Study design: A single-center retrospective study at academic NICU. Total of 391 (78 GT, 313 non-GT) infants < 30 w GA admitted in 2015–2018 split into test (15–16) and validation (17–18) cohorts. Classification and regression tree analysis was used to identify predictive factors for GT. Results: Several factors were associated with GT requirements. Four factors included in the model were postmenstrual age (PMA) at first oral feeding, birth GA, high-frequency ventilation exposure, necrotizing enterocolitis stage II/III. Area under the receiver operator characteristic curve was 0.944 in the test cohort, 0.815 in the validation cohort. Implementation plan based on the model was developed. Conclusions: We developed a predictive model to risk-stratify infants born < 30 w GA for failing full oral feeding. We hope implementation at 38 w PMA will result in earlier placement of needed GT and discharge.

Original languageEnglish (US)
Pages (from-to)126-131
Number of pages6
JournalJournal of Perinatology
Volume42
Issue number1
DOIs
StatePublished - Jan 2022

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Fingerprint

Dive into the research topics of 'A predictive model for preterm babies born < 30 weeks gestational age who will not attain full oral feedings'. Together they form a unique fingerprint.

Cite this