A pressure system for the microinjection of substances into the brain of awake monkeys

Elisa C. Dias; Mark A. Segraves

doi:10.1016/S0165-0270(96)00154-9

A pressure system for the microinjection of substances into the brain of awake monkeys

Elisa C. Dias, Mark A. Segraves^*

^*Corresponding author for this work

Neurobiology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We describe a method for placing pressure microinjections of drugs or anatomical tracers in physiologically defined sites in the brain of awake monkeys. This method provides a means to record neuronal activity from the tip of an injection cannula so that an injection can be made at a physiologically defined location. It uses pressure in a closed system to precisely control the amount of fluid injected and provides a visible means for monitoring injection volume. The injection cannula is easy to make with readily available components and can be used repeatedly for multiple recording sessions and injections.

Original language	English (US)
Pages (from-to)	43-47
Number of pages	5
Journal	Journal of Neuroscience Methods
Volume	72
Issue number	1
DOIs	https://doi.org/10.1016/S0165-0270(96)00154-9
State	Published - Mar 1 1997

Keywords

Awake behaving primate
Microinjection
Neurophysiology

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/S0165-0270(96)00154-9

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