A pressure system for the microinjection of substances into the brain of awake monkeys

Elisa C. Dias, Mark A. Segraves*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

We describe a method for placing pressure microinjections of drugs or anatomical tracers in physiologically defined sites in the brain of awake monkeys. This method provides a means to record neuronal activity from the tip of an injection cannula so that an injection can be made at a physiologically defined location. It uses pressure in a closed system to precisely control the amount of fluid injected and provides a visible means for monitoring injection volume. The injection cannula is easy to make with readily available components and can be used repeatedly for multiple recording sessions and injections.

Original languageEnglish (US)
Pages (from-to)43-47
Number of pages5
JournalJournal of Neuroscience Methods
Volume72
Issue number1
DOIs
StatePublished - Mar 1 1997

Keywords

  • Awake behaving primate
  • Microinjection
  • Neurophysiology

ASJC Scopus subject areas

  • Neuroscience(all)

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