A Proposal from the Montpellier World Health Organization Collaborating Centre for Better Management and Prevention of Anaphylaxis

Luciana Kase Tanno*, Nidhal Touati, Salome Allichon, Bryan Martin, Motohiro Ebisawa, Ignacio Ansotegui, Mario Sanchez-Borges, Victoria Cardona, Paul A. Greenberger, Dermot Ryan, Guillaume Pouessel, Etienne Beaudouin, Jean Marie Renaudin, Francis Thien, Yoon Seok Chang, Ruby Pawankar, Maximiliano Gomez, Edgardo Jares, Patricia Latour Staffeld, Ioana AgacheAntonella Muraro, Todd A. Mahr, James Sublett, Thomas Casale, David Lang, Pascal Demoly

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Since the first description of anaphylaxis in 1902, its clinical importance as an emergency condition has been recognized worldwide. Anaphylaxis is a severe, potentially life-threatening systemic hypersensitivity reaction characterized by rapid onset and the potential to endanger life through respiratory or circulatory compromise. It is usually, although not always, associated with skin and mucosal changes. Although the academic/scientific communities have advocated to promote greater awareness and protocols for the management of anaphylaxis based on best evidence, there are few efforts documenting feedback as to the success of these efforts. In this article, we review the key unmet needs related to the diagnosis and management of anaphylaxis, and propose a public health initiative for prevention measures and a timetable action plan that intends to strengthen the collaboration among health professionals and especially primary care physicians dealing with anaphylaxis, which can encourage enhanced quality of care of patients with anaphylaxis. More than calling for a harmonized action for the best management of anaphylaxis to prevent undue morbidity and mortality, the Montpellier World Health Organization Collaborating Centre here proposes an action plan as a baseline for a global initiative against anaphylaxis. We strongly believe that these collaborative efforts are a strong public health and societal priority that is consistent with the overarching goals of providing optimal care of allergic patients and best practices of allergology.

Original languageEnglish (US)
Pages (from-to)676-683.e1
JournalJournal of Allergy and Clinical Immunology: In Practice
Issue number2
StatePublished - Feb 2021


  • Adrenaline/epinephrine autoinjector
  • Anaphylaxis
  • Classification
  • Epidemiology
  • Management
  • Prevention
  • Treatment

ASJC Scopus subject areas

  • Immunology and Allergy


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