A protocol for the handling of tissue obtained by operative lung biopsy: Recommendations of the chILD pathology co-operative group

Claire Langston*, Kathleen Patterson, Megan K. Dishop, Fred Askin, Peter Baker, Pauline Chou, Carlyne Cool, Susan Coventry, Ernest Cutz, Mary Davis, Gail Deutsch, Csaba Galambos, Judy Pugh, Susan Wert, Frances White

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

90 Scopus citations


This is the first of a series on pediatric pulmonary disease that will appear as Perspectives in Pediatric Pathology over the coming months. The series will include practical issues, such as this protocol for handling lung biopsies and another on bronchoalveolar lavage in childhood, as well as reviews of advances in various areas in pediatric pulmonary pathology. It has been 11 years since the last Perspectives on pulmonary disease. Much has happened since then in this area, and this collection will highlight some emerging and rapidly advancing areas in pediatric lung disease. These will include a review of molecular mechanisms of lung development, and another of mechanisms of pulmonary vascular development. The surfactant system and its disorders, as well as recent advances in the biology of the pulmonary neuroendocrine system and mechanisms of respiratory viral disease, will be addressed. Articles on pulmonary hypertension, pulmonary neoplasia, and pediatric lung transplantation, with their implications for the pediatric pathologist, are also planned. The contributors to this series are a diverse group with special interests and expertise in these areas. As Dr. William Thurlbeck noted in his foreword to the previous volume, Pulmonary Disease, volume 18 of Perspectives in Pediatric Pathology, pediatric pathology had been largely concerned with phenomenology, rather than with mechanisms, model systems, and experimental investigation. I think he would have been pleased to see the changes that have occurred over the past 10 years in pediatric lung biology and pathology in particular, because these were particularly favored interests of his later years.

Original languageEnglish (US)
Pages (from-to)173-180
Number of pages8
JournalPediatric and Developmental Pathology
Issue number3
StatePublished - May 2006


  • Pediatric lung biopsy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine


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