A Randomized Controlled Trial of a Mobile Clinical Decision Aid to Improve Access to Kidney Transplantation: iChoose Kidney

Rachel E. Patzer*, Mohua Basu, Sumit Mohan, Kayla D. Smith, Michael S. Wolf, Daniela P. Ladner, John J. Friedewald, Mariana C. Chiles, Allison L. Russell, Laura J. McPherson, Jennifer C. Gander, Stephen O. Pastan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Introduction Kidney transplantation is the preferred treatment for patients with end-stage renal disease, as it substantially increases a patient's survival and is cost-saving compared to a lifetime of dialysis. However, transplantation is not universally chosen by patients with renal failure, and limited knowledge about the survival benefit of transplantation versus dialysis may play a role. We created a mobile application clinical decision aid called iChoose Kidney to improve access to individualized prognosis information comparing dialysis and transplantation outcomes. Methods We describe the iChoose Kidney study, a randomized controlled trial designed to test the clinical efficacy of a mobile health decision aid among end-stage renal disease patients referred for kidney transplantation at 3 large, diverse transplant centers across the United States. Approximately 450 patients will be randomized to receive either (i) standard of care or “usual” transplantation education, or (ii) standard of care plus iChoose Kidney. Results The primary outcome is change in knowledge about the survival benefit of kidney transplantation versus dialysis from baseline to immediate follow-up; secondary outcomes include change in treatment preferences, improved decisional conflict, and increased access to kidney transplantation. Analyses are also planned to examine effectiveness across subgroups of race, socioeconomic status, health literacy, and health numeracy. Discussion Engaging patients in health care choices can increase patient empowerment and improve knowledge and understanding of treatment choices. If the effectiveness of iChoose Kidney has a greater impact on patients with low health literacy, lower socioeconomic status, and minority race, this decision aid could help reduce disparities in access to kidney transplantation.

Original languageEnglish (US)
Pages (from-to)34-42
Number of pages9
JournalKidney International Reports
Issue number1
StatePublished - 2016


  • education
  • kidney transplantation
  • mobile health
  • randomized trial
  • staff

ASJC Scopus subject areas

  • Nephrology
  • Ophthalmology


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