A randomized controlled trial of the effect of combined spinal-epidural analgesia on the success of external cephalic version for breech presentation

J. T. Sullivan*, W. A. Grobman, J. R. Bauchat, B. M. Scavone, S. Grouper, R. J. McCarthy, C. A. Wong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Background: Improving the success of external cephalic version (ECV) for breech presentation may help avoid some cesarean deliveries. The results of randomized trials comparing the success of ECV with neuraxial analgesia compared to control are inconsistent. We hypothesized that combined spinal-epidural (CSE) analgesia would increase the success of ECV when compared with systemic opioid analgesia. Methods: Parturients with singleton breech presentation (n = 96) were randomized to receive CSE analgesia with bupivacaine 2.5 mg and fentanyl 15 μg (CSE group) or intravenous fentanyl 50 μg (SYS group) before ECV attempt. The primary outcome was ECV success. Results: The success rate of ECV was 47% with CSE and 31% in the SYS group (P = 0.14). Subsequent vaginal delivery was 36% for CSE and 25% for SYS (P = 0.27). Median [IQR] visual analog pain scores (0-100 mm scale) were lower with CSE (3 [0-12]) compared to SYS analgesia (36 [16 to 54]) (P < 0.005) and patient satisfaction (0-10 scale) was higher (CSE 10 [9 to 10] versus SYS 7 [4 to 9]) (P < 0.005). There were no differences in fetal heart rate patterns, but median time to return to fetal heart rate reactivity after analgesia was shorter with CSE (13 [IQR 9-21] min) compared to the SYS group (39 [IQR 23-51] min) (P = 0.02). Conclusions: There was no difference in the rate of successful ECV or vaginal delivery with CSE compared to intravenous fentanyl analgesia. Pain scores were lower and satisfaction higher with CSE analgesia, and median time to fetal heart rate reactivity was shorter in the CSE group.

Original languageEnglish (US)
Pages (from-to)328-334
Number of pages7
JournalInternational Journal of Obstetric Anesthesia
Volume18
Issue number4
DOIs
StatePublished - Oct 1 2009

Keywords

  • Breech presentation
  • Combined spinal-epidural analgesia
  • External cephalic version

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Anesthesiology and Pain Medicine

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