A Rapid and Accurate Method to Detect Active Small Bowel Gastrointestinal Bleeding on Video Capsule Endoscopy

Adam C. Stein, Anoop Appannagari, Ibrahim Habib, Carol E. Semrad, David T. Rubin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background: Video capsule endoscopy (VCE) is indicated to evaluate for suspected small bowel bleeding, but “standard view” (SV) evaluation is time-consuming. Rapid Reader 6.0 software (Given Imaging, Duluth GA) contains two computer algorithmic systems: (1) “Quickview” (QV) which automatically skips similar images and (2) a pixel analysis program that identifies suspected blood (SBI). Combining the two modalities (QV + SBI) may provide a faster modality to assess for active small bowel bleeding. Aims: This study was designed to assess the accuracy of QV + SBI for small bowel bleeding compared to SV findings. Methods: This is a retrospective, case–control study at a single tertiary care referral hospital including all patients with VCE performed for suspected small bowel bleeding from 4/2007 to 3/2011. All studies were previously read using SV by one of two experienced faculty (CS, DR). The primary outcome was diagnostic accuracy of QV + SBI in assessing for active small bowel bleeding compared to SV. Results: A total of 116 VCE were included, 28 with active small bowel bleeding identified by original SV. Using QV + SBI, all 28 VCEs with active small bowel bleeding were identified. The sensitivity of QV + SBI to detect active bleeding was 100 %, while the specificity was 93–94 %. The mean time to identify landmarks and read the entire study was 3 min 20 s. Conclusions: The QV + SBI reading format of VCE is an efficient, highly sensitive modality to assess for potential small bowel bleeding.

Original languageEnglish (US)
Pages (from-to)2503-2507
Number of pages5
JournalDigestive Diseases and Sciences
Issue number10
StatePublished - Oct 1 2014


  • Given
  • Quickview
  • Small bowel bleeding
  • Suspected blood indicator
  • Video capsule endoscopy

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology


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