A rapid method for production of binucleate cells

Lois H. Dickerman*, R. D. Goldman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Populations of BHK-21 fibroblasts that are 90-95% binucleate can be obtained within 2-3 h by combining mitotic synchrony techniques with use of the drug cytochalasin B. Such populations are potentially useful for the study of nuclear-cytoplasmic balance and control, nuclear synchrony, and the production of tetraploid cell lines.

Original languageEnglish (US)
Pages (from-to)433-436
Number of pages4
JournalExperimental Cell Research
Issue number2
StatePublished - Feb 1974

ASJC Scopus subject areas

  • Cell Biology


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