TY - JOUR
T1 - A review on recent advancements in ophthalmology devices
T2 - Currently in market and under clinical trials
AU - Nagaraj, Rajini
AU - Bijukumar, Divya Rani
AU - Mathew, Benjamin
AU - Scott, Evan A.
AU - Mathew, Mathew T.
N1 - Funding Information:
The authors acknowledge the Blazer Foundation for supporting the Regenerative Medicine and Disability (RMDR) Lab at the Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford. The financial support from the MBT program at the Department of Biomedical Science is also acknowledged.
Publisher Copyright:
© 2019 Elsevier B.V.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/8
Y1 - 2019/8
N2 - The complex anatomical features of the eye and the presence of different ocular barriers has led to complications in the development of an effective treatment strategy for posterior segment diseases like diabetic retinopathy, age-related macular degeneration, retinal pigmentosa, etc., thus demanding the need for novel and innovative approaches. There are various treatment options available in the market which includes the new implants and drug delivery systems apart from the therapeutic agents which are benefiting the patients with modern improvements, enhanced formulations, targeted and long-term delivery. But they all still have numerous drawbacks which need to be addressed. This review article discusses and highlights the recent developments made in the ophthalmology which are in the market currently and under clinical trial. This review also suggests a possible alternative system that can be an effective and practical option for the treatment of posterior segment ophthalmic diseases.
AB - The complex anatomical features of the eye and the presence of different ocular barriers has led to complications in the development of an effective treatment strategy for posterior segment diseases like diabetic retinopathy, age-related macular degeneration, retinal pigmentosa, etc., thus demanding the need for novel and innovative approaches. There are various treatment options available in the market which includes the new implants and drug delivery systems apart from the therapeutic agents which are benefiting the patients with modern improvements, enhanced formulations, targeted and long-term delivery. But they all still have numerous drawbacks which need to be addressed. This review article discusses and highlights the recent developments made in the ophthalmology which are in the market currently and under clinical trial. This review also suggests a possible alternative system that can be an effective and practical option for the treatment of posterior segment ophthalmic diseases.
KW - Electronic retinal implants
KW - Nanoparticle drug delivery systems
KW - Ocular diseases
KW - Ocular drug delivery
KW - Ophthalmic devices
KW - Ophthalmic implants
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U2 - 10.1016/j.jddst.2019.04.038
DO - 10.1016/j.jddst.2019.04.038
M3 - Review article
AN - SCOPUS:85065137402
VL - 52
SP - 334
EP - 345
JO - Journal of Drug Delivery Science and Technology
JF - Journal of Drug Delivery Science and Technology
SN - 1773-2247
ER -
