A rotaxane-like complex with controlled-release characteristics

Sheng Hsien Chiu; Stuart J. Rowan; Stuart J. Cantrill; Peter T. Glink; Robin L. Garrell; J. Fraser Stoddart

doi:10.1021/ol006525d

A rotaxane-like complex with controlled-release characteristics

Sheng Hsien Chiu, Stuart J. Rowan, Stuart J. Cantrill, Peter T. Glink, Robin L. Garrell, J. Fraser Stoddart^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

(matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH₂⁺ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a "threading-followed-by-stoppering" approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.

Original language	English (US)
Pages (from-to)	3631-3634
Number of pages	4
Journal	Organic Letters
Volume	2
Issue number	23
DOIs	https://doi.org/10.1021/ol006525d
State	Published - Nov 16 2000

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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title = "A rotaxane-like complex with controlled-release characteristics",

abstract = "(matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH2+ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a {"}threading-followed-by-stoppering{"} approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.",

author = "Chiu, {Sheng Hsien} and Rowan, {Stuart J.} and Cantrill, {Stuart J.} and Glink, {Peter T.} and Garrell, {Robin L.} and Stoddart, {J. Fraser}",

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language = "English (US)",

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T1 - A rotaxane-like complex with controlled-release characteristics

AU - Chiu, Sheng Hsien

AU - Rowan, Stuart J.

AU - Cantrill, Stuart J.

AU - Glink, Peter T.

AU - Garrell, Robin L.

AU - Stoddart, J. Fraser

PY - 2000/11/16

Y1 - 2000/11/16

N2 - (matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH2+ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a "threading-followed-by-stoppering" approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.

AB - (matrix presented) A rotaxane-like complex, based on a dumbbell-shaped component containing an NH2+ recognition site for a [25]crown-8 ring component and a slippage stopper in the form of a p-(tert-butyl)phenyl group, has been synthesized by a "threading-followed-by-stoppering" approach. The half-life for dissociation of this complex, which is very sensitive to its environment, can be varied from minutes to months by changing the temperature and the polarity of the solvent.

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JO - Organic Letters

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ER -

A rotaxane-like complex with controlled-release characteristics

Abstract

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