TY - JOUR
T1 - A signaling pathway governing early thymocyte maturation
AU - Anderson, Steven J.
AU - Perlmutter, Roger M.
N1 - Funding Information:
Work described in this article was supported in part by a grant from the NIH (CA-45682). We thank Kathi Prewitt for secretarial assistance, and our colleagues for helpful discussions. RMP is an Investigator of the Howard Hughes Medical Institute.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1995
Y1 - 1995
N2 - Recent evidence supports the view that p56lck, a non-receptor protein tyrosine kinase, serves as the signaling element that 'senses' synthesis of a functional T-cell receptor β chain, thereby promoting thymocyte maturation. Here, Steven Anderson and Roger Perlmutter review current data, and outline the features of this developmental program.
AB - Recent evidence supports the view that p56lck, a non-receptor protein tyrosine kinase, serves as the signaling element that 'senses' synthesis of a functional T-cell receptor β chain, thereby promoting thymocyte maturation. Here, Steven Anderson and Roger Perlmutter review current data, and outline the features of this developmental program.
UR - http://www.scopus.com/inward/record.url?scp=0028830744&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028830744&partnerID=8YFLogxK
U2 - 10.1016/0167-5699(95)80096-4
DO - 10.1016/0167-5699(95)80096-4
M3 - Article
C2 - 7888074
AN - SCOPUS:0028830744
VL - 16
SP - 99
EP - 105
JO - Trends in Immunology
JF - Trends in Immunology
SN - 1471-4906
IS - 2
ER -