Abstract
Recent evidence supports the view that p56lck, a non-receptor protein tyrosine kinase, serves as the signaling element that 'senses' synthesis of a functional T-cell receptor β chain, thereby promoting thymocyte maturation. Here, Steven Anderson and Roger Perlmutter review current data, and outline the features of this developmental program.
Original language | English (US) |
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Pages (from-to) | 99-105 |
Number of pages | 7 |
Journal | Immunology Today |
Volume | 16 |
Issue number | 2 |
DOIs | |
State | Published - 1995 |
ASJC Scopus subject areas
- Immunology