A simple sheath-flow microfluidic device for micro/nanomanufacturing: Fabrication of hydrodynamically shaped polymer fibers

Abel L. Thangawng; Peter B. Howell; Jeffrey J. Richards; Jeffrey S. Erickson; Frances S. Ligler

doi:10.1039/b910581f

A simple sheath-flow microfluidic device for micro/nanomanufacturing: Fabrication of hydrodynamically shaped polymer fibers

Abel L. Thangawng, Peter B. Howell, Jeffrey J. Richards, Jeffrey S. Erickson, Frances S. Ligler

Chemical and Biological Engineering

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

A simple sheath flow microfluidic device is used to fabricate polymer micro/nanofibers that have precisely controlled shapes and sizes. Poly(methylmethacrylate) (PMMA) was used as the model polymer for these experiments. The sheath-flow device uses straight diagonal and chevron-shaped grooves integrated in the top and bottom walls of the flow channel to move sheath fluid completely around the polymer stream. Portions of the sheath stream are deflected in such a way as to define the cross-sectional shape of the polymer core. The flow-rate ratio between the sheath and core solution determines the fiber diameter. Round PMMA fibers with a diameter as small as 300 nm and flattened fibers with a submicron thickness are demonstrated.

Original language	English (US)
Pages (from-to)	3126-3130
Number of pages	5
Journal	Lab on a Chip
Volume	9
Issue number	21
DOIs	https://doi.org/10.1039/b910581f
State	Published - 2009

ASJC Scopus subject areas

Bioengineering
Biochemistry
Chemistry(all)
Biomedical Engineering

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10.1039/b910581f

Cite this

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A simple sheath-flow microfluidic device for micro/nanomanufacturing: Fabrication of hydrodynamically shaped polymer fibers

Abstract

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