A small catalytic oligoribonucleotide

Olke C. Uhlenbeck

doi:10.1038/328596a0

A small catalytic oligoribonucleotide

Olke C. Uhlenbeck^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Article › peer-review

903 Scopus citations

Abstract

A 19-nucleotide RNA fragment can cause rapid, highly specific cleavage of a 24-nucleotide RNA fragment under physiological conditions. Because each 19-mer can participate in many cleavage reactions, this molecule has all the properties associated with an RNA enzyme.

Original language	English (US)
Pages (from-to)	596-600
Number of pages	5
Journal	Nature
Volume	328
Issue number	6131
DOIs	https://doi.org/10.1038/328596a0
State	Published - 1988

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title = "A small catalytic oligoribonucleotide",

abstract = "A 19-nucleotide RNA fragment can cause rapid, highly specific cleavage of a 24-nucleotide RNA fragment under physiological conditions. Because each 19-mer can participate in many cleavage reactions, this molecule has all the properties associated with an RNA enzyme.",

author = "Uhlenbeck, {Olke C.}",

year = "1988",

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pages = "596--600",

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PY - 1988

Y1 - 1988

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AB - A 19-nucleotide RNA fragment can cause rapid, highly specific cleavage of a 24-nucleotide RNA fragment under physiological conditions. Because each 19-mer can participate in many cleavage reactions, this molecule has all the properties associated with an RNA enzyme.

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A small catalytic oligoribonucleotide

Abstract

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