Abstract
Surfing with the kinase: A soluble kinase phosphorylates an immobilized peptide substrate most rapidly at the boundary between product and substrate, and gives rise to a "wave" of propagating product. Such systems offer an approach to engineering reactions to give spatio-temporal control over progression of reactions.
Original language | English (US) |
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Pages (from-to) | 706-708 |
Number of pages | 3 |
Journal | Angewandte Chemie - International Edition |
Volume | 50 |
Issue number | 3 |
DOIs | |
State | Published - Jan 17 2011 |
Keywords
- adaptor domains
- autocatalysis
- monolayers
- phosphorylation
- propagation
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)