TY - JOUR
T1 - A specialized multi-disciplinary care program for children with sepsis and multiple organ dysfunction-associated immune dysregulation
AU - Swigart, Lindsey R.
AU - Sanchez-Pinto, L. Nelson
AU - Nolan, Brian E.
AU - Seed, Patrick C.
AU - Coates, Bria M.
N1 - Funding Information:
The authors would like to acknowledge the support of the entire PrIIMe team in the creation and success of this program, including Aisha Ahmed, Amer Khojah, Joanna Weinstein, Leena Mithal, Taylor Heald-Sargent, Allison Remiker, Ravi Jhaveri, Ami Patel, Mehreen Arshad, and Jeffery Brown. We would also like to acknowledge the Lurie Children’s Immunology Lab including Aaruni Khanolkhar and Nicolas Benson, and the Lurie Children’s Genetics Division, including Kai Lee Yap and Alexander Ing for supporting the diagnostics arm of the team. We would like to thank all the patients and families cared for by the PrIIMe team for allowing us to be a part of their medical experience and teaching us every day.
Publisher Copyright:
© 2022, The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc.
PY - 2022/1
Y1 - 2022/1
N2 - Abstract: The complex physiology and medical requirements of children with sepsis and multiple organ dysfunction syndrome (MODS) challenge traditional care coordination models. While the involvement of multiple clinical subspecialty services is often necessary to support different care processes and individual organ system dysfunctions, it can also delay the diagnostic process, monitoring, and treatment. The logistics of coordinating with many specialty providers for critically ill patients are challenging and time consuming, and often can result in fragmented communication. To address these and other related issues, we developed a new multi-disciplinary consult service focused on streamlining diagnostics, management, and communication for patients with sepsis and MODS-associated immune dysregulation. The service, called the Program in Inflammation, Immunity, and the Microbiome (PrIIMe), is now a hospital-wide clinical consult service at our institution caring for a broad group of patients with immune dysregulation, particularly focusing on patients with sepsis and MODS. In this paper, we summarize the development, structure, and function of the program, as well as the initial impact. This information may be helpful to clinicians and healthcare leaders who are developing multi-disciplinary consult services for children with complex care needs, especially those with sepsis and MODS-associated immune dysregulation. Impact: The care of children with sepsis and multiple organ dysfunction-associated immune dysregulation requires rapid and flexible involvement of multiple clinical subspecialists that is difficult to achieve without fragmented care and delayed decision making.In this narrative review we describe the development, structure, and function of a multi-disciplinary consult service at a children’s hospital dedicated to helping coordinate management and provide continuity of care for patients with sepsis and multiple organ dysfunction-associated immune dysregulation.This information may be helpful to clinicians and healthcare leaders who are developing multi-disciplinary consult services for children with complex care needs, especially those with sepsis and MODS-associated immune dysregulation.
AB - Abstract: The complex physiology and medical requirements of children with sepsis and multiple organ dysfunction syndrome (MODS) challenge traditional care coordination models. While the involvement of multiple clinical subspecialty services is often necessary to support different care processes and individual organ system dysfunctions, it can also delay the diagnostic process, monitoring, and treatment. The logistics of coordinating with many specialty providers for critically ill patients are challenging and time consuming, and often can result in fragmented communication. To address these and other related issues, we developed a new multi-disciplinary consult service focused on streamlining diagnostics, management, and communication for patients with sepsis and MODS-associated immune dysregulation. The service, called the Program in Inflammation, Immunity, and the Microbiome (PrIIMe), is now a hospital-wide clinical consult service at our institution caring for a broad group of patients with immune dysregulation, particularly focusing on patients with sepsis and MODS. In this paper, we summarize the development, structure, and function of the program, as well as the initial impact. This information may be helpful to clinicians and healthcare leaders who are developing multi-disciplinary consult services for children with complex care needs, especially those with sepsis and MODS-associated immune dysregulation. Impact: The care of children with sepsis and multiple organ dysfunction-associated immune dysregulation requires rapid and flexible involvement of multiple clinical subspecialists that is difficult to achieve without fragmented care and delayed decision making.In this narrative review we describe the development, structure, and function of a multi-disciplinary consult service at a children’s hospital dedicated to helping coordinate management and provide continuity of care for patients with sepsis and multiple organ dysfunction-associated immune dysregulation.This information may be helpful to clinicians and healthcare leaders who are developing multi-disciplinary consult services for children with complex care needs, especially those with sepsis and MODS-associated immune dysregulation.
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U2 - 10.1038/s41390-021-01891-y
DO - 10.1038/s41390-021-01891-y
M3 - Review article
C2 - 35022559
AN - SCOPUS:85122689941
SN - 0031-3998
VL - 91
SP - 464
EP - 469
JO - Pediatric research
JF - Pediatric research
IS - 2
ER -