A structurally simple minimal self-replicating system

Julie M. Quayle; Alexandra M.Z. Slawin; Douglas Philp

doi:10.1016/S0040-4039(02)01613-1

A structurally simple minimal self-replicating system

Julie M. Quayle, Alexandra M.Z. Slawin, Douglas Philp^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Molecular recognition between an amidopyridine and a carboxylic acid through two complementary hydrogen bonding sites renders the reaction between an azide and a maleimide self-replicating, but not autocatalytic.

Original language	English (US)
Pages (from-to)	7229-7233
Number of pages	5
Journal	Tetrahedron Letters
Volume	43
Issue number	40
DOIs	https://doi.org/10.1016/S0040-4039(02)01613-1
State	Published - Sep 30 2002

Funding

This work was supported by the Engineering and Physical Sciences Research Council (Quota Award to J.M.Q.), the Biotechnology and Biological Sciences Research Council (Grant B6/11855) and the University of St Andrews. We thank Professor G. von Kiedrowski for providing us with a copy of his SimFit program.

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(02)01613-1

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title = "A structurally simple minimal self-replicating system",

abstract = "Molecular recognition between an amidopyridine and a carboxylic acid through two complementary hydrogen bonding sites renders the reaction between an azide and a maleimide self-replicating, but not autocatalytic.",

author = "Quayle, {Julie M.} and Slawin, {Alexandra M.Z.} and Douglas Philp",

note = "Funding Information: This work was supported by the Engineering and Physical Sciences Research Council (Quota Award to J.M.Q.), the Biotechnology and Biological Sciences Research Council (Grant B6/11855) and the University of St Andrews. We thank Professor G. von Kiedrowski for providing us with a copy of his SimFit program. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

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AU - Quayle, Julie M.

AU - Slawin, Alexandra M.Z.

AU - Philp, Douglas

N1 - Funding Information: This work was supported by the Engineering and Physical Sciences Research Council (Quota Award to J.M.Q.), the Biotechnology and Biological Sciences Research Council (Grant B6/11855) and the University of St Andrews. We thank Professor G. von Kiedrowski for providing us with a copy of his SimFit program. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2002/9/30

Y1 - 2002/9/30

N2 - Molecular recognition between an amidopyridine and a carboxylic acid through two complementary hydrogen bonding sites renders the reaction between an azide and a maleimide self-replicating, but not autocatalytic.

AB - Molecular recognition between an amidopyridine and a carboxylic acid through two complementary hydrogen bonding sites renders the reaction between an azide and a maleimide self-replicating, but not autocatalytic.

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U2 - 10.1016/S0040-4039(02)01613-1

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ER -

A structurally simple minimal self-replicating system

Abstract

Funding

ASJC Scopus subject areas

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