A sugar that benefits failing hearts

J. A. St.Cyr*, Joseph R. Schneider

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Ischemia is a major etiological factor in the development and progression of congestive heart failure. Current pharmaceutical treatments do not address the underlying metabolic problem within the heart. Adenosine triphosphate levels, critical for the preservation of cellular integrity, intracellular enzymatic reactions, and function, are depleted with myocardial ischemia, and in heart failure as well. Future therapies should look to enhance myocardial energy metabolism in the failing heart.

Original languageEnglish (US)
Pages (from-to)398
Number of pages1
JournalInternational Journal of Cardiology
Volume131
Issue number3
DOIs
StatePublished - Jan 24 2009

Keywords

  • Congestive heart failure
  • Ischemia
  • Ribose

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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