A sugar that benefits failing hearts

J. A. St.Cyr; Joseph R. Schneider

doi:10.1016/j.ijcard.2007.08.012

A sugar that benefits failing hearts

J. A. St.Cyr^*, Joseph R. Schneider

^*Corresponding author for this work

Surgery, Vascular Surgery Division

Research output: Contribution to journal › Article › peer-review

Abstract

Ischemia is a major etiological factor in the development and progression of congestive heart failure. Current pharmaceutical treatments do not address the underlying metabolic problem within the heart. Adenosine triphosphate levels, critical for the preservation of cellular integrity, intracellular enzymatic reactions, and function, are depleted with myocardial ischemia, and in heart failure as well. Future therapies should look to enhance myocardial energy metabolism in the failing heart.

Original language	English (US)
Pages (from-to)	398
Number of pages	1
Journal	International Journal of Cardiology
Volume	131
Issue number	3
DOIs	https://doi.org/10.1016/j.ijcard.2007.08.012
State	Published - Jan 24 2009

Keywords

Congestive heart failure
Ischemia
Ribose

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/j.ijcard.2007.08.012

Cite this

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AB - Ischemia is a major etiological factor in the development and progression of congestive heart failure. Current pharmaceutical treatments do not address the underlying metabolic problem within the heart. Adenosine triphosphate levels, critical for the preservation of cellular integrity, intracellular enzymatic reactions, and function, are depleted with myocardial ischemia, and in heart failure as well. Future therapies should look to enhance myocardial energy metabolism in the failing heart.

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KW - Ribose

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A sugar that benefits failing hearts

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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